PENGARUH PERBANDINGAN KONSENTRASI FASE MINYAK SALEP EKSTRAK IKAN GABUS (Channa striata) TERHADAP LAMA PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH GALUR WISTAR (Rattus norvegicus)

  • KHAIRUNNISA KHAIRUNNISA FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA
Keywords: Chianna striata, Wounds, Ointment

Abstract

Fish is one of the largest natural resources in Indonesia which is useful as a source of protein and a source of natural medicinal ingredients, one of which is snakehead fish. Empirically, snakehead fish is often consumed as a side dish after childbirth and as a medicine for wounds caused by sharp objects. Wounds are the loss or destruction of part of the body's tissues. This condition can be caused by sharp or blunt trauma, temperature changes, chemicals, explosions, electric shocks, or animal bites. The wound healing process is not only limited to local regeneration processes, but is also influenced by endogenous factors, such as age, nutrition, immunology, use of drugs, and metabolic conditions. During the healing process, adequate intake of nutrients such as carbohydrates, protein, fat and micronutrients. Therefore, it is necessary to conduct a study to see the concentration of snakehead fish (Channa striata) extract oil phase ointment which has the greatest effect in accelerating the healing process of cuts in white rats of Wistar strain (Rattus norvegicus). Objective: To determine the effective concentration of snakehead fish (Channa striata) oil phase ointment on the healing time of cuts in white rats of Wistar strain (Rattus norvegicus). The research method is a True Experiment with Post-test Only with Control Group Design. The sampling technique used is simple random sampling where the sample subject is selected by means of each subject being numbered and some of them are selected with the help of a random number table. The results are known that p value >0.05 was found between the negative control group and the 20% concentration group, the p value <0.05 between the negative control group and the 40% concentration group, the p value <0.05 between the 20% concentration group and the 40% concentration group. That is, snakehead fish ointment with a concentration of 40% has the highest effectiveness. The conclusion of this research is The increase in the concentration of snakehead fish (Channa striata) oil phase ointment was directly proportional to the speed of wound healing.

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Published
2022-12-17
How to Cite
KHAIRUNNISA, K. (2022). PENGARUH PERBANDINGAN KONSENTRASI FASE MINYAK SALEP EKSTRAK IKAN GABUS (Channa striata) TERHADAP LAMA PENYEMBUHAN LUKA SAYAT PADA TIKUS PUTIH GALUR WISTAR (Rattus norvegicus). JURNAL ILMIAH MAKSITEK, 7(4), 33-37. Retrieved from https://makarioz.sciencemakarioz.org/index.php/JIM/article/view/352